Critical Function of PRDM2 in the Neoplastic Growth of Testicular Germ Cell Tumors

Testicular germ cell tumors (TGCTs) derive from primordial germ cells. Their maturation is blocked at different stages, reflecting histological tumor subtypes. A common genetic alteration in TGCT is a deletion of the chromosome 1 short arm, where the PRDM2 gene, belonging to the Positive Regulatory...

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Bibliographic Details
Main Authors: Erika Di Zazzo, Carola Porcile, Silvia Bartollino, Bruno Moncharmont
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Biology
Subjects:
Online Access:http://www.mdpi.com/2079-7737/5/4/54