Chemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signalling.

Understanding the molecular mechanism of signalling in the important super-family of G-protein-coupled receptors (GPCRs) is causally related to questions of how and where these receptors can be activated or inhibited. In this context, it is of great interest to unravel the common molecular features...

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Bibliographic Details
Main Authors: Jörg D Wichard, Antonius Ter Laak, Gerd Krause, Nikolaus Heinrich, Ronald Kühne, Gunnar Kleinau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3033908?pdf=render