Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion Sarcoma

Epithelioid hemangioendothelioma (EHE) is a rare soft-tissue sarcoma involving cells with histologic markers that suggest an endothelial origin. Around 90% of EHEs are caused by the fusion of Transcriptional Co-activator with a PDZ-motif (TAZ) with Calmodulin Binding Transcription Activator 1 (CAMTA...

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Bibliographic Details
Main Authors: John M. Lamar, Vijeyaluxmy Motilal Nehru, Guy Weinberg
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Cancers
Subjects:
TAZ
YAP
Online Access:http://www.mdpi.com/2072-6694/10/7/229