Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1

Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1

Abstract Vectored gene delivery of HIV-1 broadly neutralizing antibodies (bNAbs) using recombinant adeno-associated virus (rAAV) is a promising alternative to conventional vaccines for preventing new HIV-1 infections and for therapeutically suppressing established HIV-1 infections. Passive infusion...

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Bibliographic Details
Main Authors: Allen Lin, Alejandro B. Balazs
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Retrovirology
Subjects:
Vectored delivery
Antibody gene transfer
AAV
HIV-1
bNAb
Clinical trials
Online Access:http://link.springer.com/article/10.1186/s12977-018-0449-7

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http://link.springer.com/article/10.1186/s12977-018-0449-7

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