Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors

Abstract Human induced pluripotent stem cells (hiPSCs) have generated a great deal of attention owing to their capacity for self‐renewal and differentiation into the three germ layers of the body. Their discovery has facilitated a new era in biomedicine for understanding human development, drug scre...

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Bibliographic Details
Main Authors: Breanna S. Borys, Tania So, James Colter, Tiffany Dang, Erin L. Roberts, Tamas Revay, Leila Larijani, Roman Krawetz, Ian Lewis, Bob Argiropoulos, Derrick E. Rancourt, Sunghoon Jung, Yas Hashimura, Brian Lee, Michael S. Kallos
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Stem Cells Translational Medicine
Subjects:
bioreactor
expansion
human induced pluripotent stem cells (hiPSCs)
low‐shear
serial‐passage
Online Access:https://doi.org/10.1002/sctm.19-0406

Internet

https://doi.org/10.1002/sctm.19-0406

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