Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.

The interaction between follicular T helper cells (TFH) and B cells in the lymph nodes and spleen has a major impact on the development of antigen-specific B cell responses during infection or vaccination. Recent studies described a functional equivalent of these cells among circulating CD4 T cells,...

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Bibliographic Details
Main Authors: Kristin L Boswell, Robert Paris, Eli Boritz, David Ambrozak, Takuya Yamamoto, Sam Darko, Kaska Wloka, Adam Wheatley, Sandeep Narpala, Adrian McDermott, Mario Roederer, Richard Haubrich, Mark Connors, Julie Ake, Daniel C Douek, Jerome Kim, Constantinos Petrovas, Richard A Koup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3911819?pdf=render

Internet

http://europepmc.org/articles/PMC3911819?pdf=render

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