Quantifying the Role of Stochasticity in the Development of Autoimmune Disease

In this paper, we propose and analyse a mathematical model for the onset and development of autoimmune disease, with particular attention to stochastic effects in the dynamics. Stability analysis yields parameter regions associated with normal cell homeostasis, or sustained periodic oscillations. Va...

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Bibliographic Details
Main Authors: Lindsay B. Nicholson, Konstantin B. Blyuss, Farzad Fatehi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/860