Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins

Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins

Abstract The emergence of SARS-CoV-2 has resulted in the COVID-19 pandemic, leading to millions of infections and hundreds of thousands of human deaths. The efficient replication and population spread of SARS-CoV-2 indicates an effective evasion of human innate immune responses, although the viral p...

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Bibliographic Details
Main Authors: Yajuan Rui, Jiaming Su, Si Shen, Ying Hu, Dingbo Huang, Wenwen Zheng, Meng Lou, Yifei Shi, Meng Wang, Shiqi Chen, Na Zhao, Qi Dong, Yong Cai, Rongzhen Xu, Shu Zheng, Xiao-Fang Yu
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00515-5

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