A structurally informed autotransporter platform for efficient heterologous protein secretion and display

A structurally informed autotransporter platform for efficient heterologous protein secretion and display

<p>Abstract</p> <p>Background</p> <p>The self-sufficient autotransporter (AT) pathway, ubiquitous in Gram-negative bacteria, combines a relatively simple protein secretion mechanism with a high transport capacity. ATs consist of a secreted passenger domain and a β-domai...

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Bibliographic Details
Main Authors: Jong Wouter SP, Soprova Zora, de Punder Karin, ten Hagen-Jongman Corinne M, Wagner Samuel, Wickström David, de Gier Jan-Willem, Andersen Peter, van der Wel Nicole N, Luirink Joen
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Microbial Cell Factories
Subjects:
Autotransporter
Type V secretion
Hemoglobin protease
Extracellular expression
Surface display
Live vaccine
Online Access:http://www.microbialcellfactories.com/content/11/1/85

Internet

http://www.microbialcellfactories.com/content/11/1/85

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