Post-Adipose-Derived Stem Cells (ADSC) Stimulated by Collagen Type V (Col V) Mitigate the Progression of Osteoarthritic Rabbit Articular Cartilage

Post-Adipose-Derived Stem Cells (ADSC) Stimulated by Collagen Type V (Col V) Mitigate the Progression of Osteoarthritic Rabbit Articular Cartilage

Collagen is essential for cartilage adhesion and formation. In the present study, histology, immunofluorescence, morphometry, and qRT-PCR suggested that adipose-derived stem cells (ADSCs) stimulated by type V collagen (Col V) induce a significant increase of type II collagen (Col II) in the degenera...

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Bibliographic Details
Main Authors: Isabele Camargo Brindo da Cruz, Ana Paula Pereira Velosa, Solange Carrasco, Antonio dos Santos Filho, Jurandir Tomaz de Miranda, Eduardo Pompeu, Tiago Lazzaretti Fernandes, Daniela Franco Bueno, Camila Fanelli, Cláudia Goldenstein-Schainberg, Alexandre Todorovic Fabro, Ricardo Fuller, Pedro Leme Silva, Vera Luiza Capelozzi, Walcy Rosolia Teodoro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
adipose-derived stem cells
collagen V
osteoarthritis
experimental model
cartilage treatment
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.606890/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.606890/full

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