Method of targeted bisulfite massive parallel sequencing of the human LINE-1 retrotransposon promoter

Method of targeted bisulfite massive parallel sequencing of the human LINE-1 retrotransposon promoter

The methylation index of the LINE-1 promoter is one of the most commonly used markers for assessing the global level of genome methylation in various human cells and tissues. We developed an NGS-based protocol for DNA methylation analysis of the LINE-1 retrotransposon promoter. This approach allows...

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Bibliographic Details
Main Authors: Stanislav A. Vasilyev, Anton V. Markov, Oksana Yu. Vasilyeva, Ekaterina N. Tolmacheva, Lada A. Zatula, Diana V. Sharysh, Daria I. Zhigalina, Victoria V. Demeneva, Igor N. Lebedev
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:MethodsX
Subjects:
NGS-based LINE-1 retrotransposon methylation analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016121002387

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http://www.sciencedirect.com/science/article/pii/S2215016121002387

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