Deferoxamine preconditioning ameliorates mechanical ventilation-induced lung injury in rat model via ROS in alveolar macrophages: a randomized controlled study

Deferoxamine preconditioning ameliorates mechanical ventilation-induced lung injury in rat model via ROS in alveolar macrophages: a randomized controlled study

Abstract Background Mechanical ventilation (MV) can provide effective breathing support; however, ventilatior-induced lung injury (VILI) has also been widely recognized in clinical practice, including in the healthy lung. Unfortunately, the morbidity and mortality of VILI remain unacceptably high, a...

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Bibliographic Details
Main Authors: Weilin Zhu, Yuansi Huang, Yuqiong Ye, Yafeng Wang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Anesthesiology
Subjects:
Ventilator-induced lung injury
Deferoxamine
Reactive oxygen species
Mitochondria
Alveolar macrophages
Online Access:http://link.springer.com/article/10.1186/s12871-018-0576-7

Internet

http://link.springer.com/article/10.1186/s12871-018-0576-7

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