Nucleation of biomimetic hydroxyapatite
Introduction. The aim of the study was to assess the formation of biomimetic calcium hydroxyapatite (HAP) on the surface of different substrates. Material and Methods. Silica coated stainless steel tapes and thin polymer films (alginate, cellulose, poly lactide-co-glycolide - PLGA) deposited on...
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Serbian Medical Society - Dental Section, Belgrade
2011-01-01
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Online Access: | http://www.doiserbia.nb.rs/img/doi/0039-1743/2011/0039-17431101007C.pdf |
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doaj-13f60ea8db1c45cc92bb927cbd36620a2020-11-24T21:36:14ZengSerbian Medical Society - Dental Section, BelgradeStomatološki glasnik Srbije0039-17432011-01-0158171510.2298/SGS1101007CNucleation of biomimetic hydroxyapatiteČolović BožanaMarković DejanJokanović VukomanIntroduction. The aim of the study was to assess the formation of biomimetic calcium hydroxyapatite (HAP) on the surface of different substrates. Material and Methods. Silica coated stainless steel tapes and thin polymer films (alginate, cellulose, poly lactide-co-glycolide - PLGA) deposited on hydroxyapatite scaffold were used as substrate. Supersaturated simulated body fluid (SBF) and SBF combined with Fetal Calf Serum (FCS) or Eagle’s Minimum Essential Medium (EMEM) were used as bioactive liquid medium where biomimetic nucleation of HAP occurred. Infrared spectroscopy with Fourier transformation was used to analyze the formed phases, while scanning electron microscopy indicated the morphology of nucleated phase. Results. The results of measuring the mass with volume adjustments done by the BET method showed that the thickness of the film of nucleated calcium hydroxyapatite depended on the time that samples spent soaked in SBF-in as well as the type of selected biomimetic medium. Conclusion. Biomimetic calcium hydroxyapatite is possible to produce by self nucleation on different substrates in the presence of simulating body fluid. http://www.doiserbia.nb.rs/img/doi/0039-1743/2011/0039-17431101007C.pdfbiomimetic methodbioactive thin filmsbiomimetic hydroxyapatitenanostructure design |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Čolović Božana Marković Dejan Jokanović Vukoman |
spellingShingle |
Čolović Božana Marković Dejan Jokanović Vukoman Nucleation of biomimetic hydroxyapatite Stomatološki glasnik Srbije biomimetic method bioactive thin films biomimetic hydroxyapatite nanostructure design |
author_facet |
Čolović Božana Marković Dejan Jokanović Vukoman |
author_sort |
Čolović Božana |
title |
Nucleation of biomimetic hydroxyapatite |
title_short |
Nucleation of biomimetic hydroxyapatite |
title_full |
Nucleation of biomimetic hydroxyapatite |
title_fullStr |
Nucleation of biomimetic hydroxyapatite |
title_full_unstemmed |
Nucleation of biomimetic hydroxyapatite |
title_sort |
nucleation of biomimetic hydroxyapatite |
publisher |
Serbian Medical Society - Dental Section, Belgrade |
series |
Stomatološki glasnik Srbije |
issn |
0039-1743 |
publishDate |
2011-01-01 |
description |
Introduction. The aim of the study was to assess the formation of biomimetic calcium hydroxyapatite (HAP) on the surface of different substrates. Material and Methods. Silica coated stainless steel tapes and thin polymer films (alginate, cellulose, poly lactide-co-glycolide - PLGA) deposited on hydroxyapatite scaffold were used as substrate. Supersaturated simulated body fluid (SBF) and SBF combined with Fetal Calf Serum (FCS) or Eagle’s Minimum Essential Medium (EMEM) were used as bioactive liquid medium where biomimetic nucleation of HAP occurred. Infrared spectroscopy with Fourier transformation was used to analyze the formed phases, while scanning electron microscopy indicated the morphology of nucleated phase. Results. The results of measuring the mass with volume adjustments done by the BET method showed that the thickness of the film of nucleated calcium hydroxyapatite depended on the time that samples spent soaked in SBF-in as well as the type of selected biomimetic medium. Conclusion. Biomimetic calcium hydroxyapatite is possible to produce by self nucleation on different substrates in the presence of simulating body fluid. |
topic |
biomimetic method bioactive thin films biomimetic hydroxyapatite nanostructure design |
url |
http://www.doiserbia.nb.rs/img/doi/0039-1743/2011/0039-17431101007C.pdf |
work_keys_str_mv |
AT colovicbozana nucleationofbiomimetichydroxyapatite AT markovicdejan nucleationofbiomimetichydroxyapatite AT jokanovicvukoman nucleationofbiomimetichydroxyapatite |
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