EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells

Interleukin 9 (IL-9) producing helper T cells (Th) have established roles in a range of inflammatory conditions and a number of transcription factors have been shown crucial for the generation of these IL-9 producing cells. Here, the authors establish a role for the EGFR-HIF1α axis in the regulation...

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Bibliographic Details
Main Authors: Suyasha Roy, Zaigham Abbas Rizvi, Alexander J. Clarke, Felicity Macdonald, Abhaydeep Pandey, Dietmar Martin Werner Zaiss, Anna Kathrina Simon, Amit Awasthi
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23042-x

Internet

https://doi.org/10.1038/s41467-021-23042-x

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