Polymorphism of human haptoglobin and its clinical importance
Haptoglobin (Hp) is a plasma glycoprotein, the main biological function of which is to bind free hemoglobin (Hb) and prevent the loss of iron and subsequent kidney damage following intravascular hemolysis. Haptoglobin is also a positive acute-phase protein with immunomodulatory properties. In humans...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Genética
2008-01-01
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Series: | Genetics and Molecular Biology |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400002 |