Polymorphism of human haptoglobin and its clinical importance

Haptoglobin (Hp) is a plasma glycoprotein, the main biological function of which is to bind free hemoglobin (Hb) and prevent the loss of iron and subsequent kidney damage following intravascular hemolysis. Haptoglobin is also a positive acute-phase protein with immunomodulatory properties. In humans...

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Bibliographic Details
Main Authors: Vânia Peretti de Albuquerque Wobeto, Tânia Regina Zaccariotto, Maria de Fátima Sonati
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2008-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000400002