Sepsis otopathy: experimental sepsis leads to significant hearing impairment due to apoptosis and glutamate excitotoxicity in murine cochlea

SUMMARY Hearing loss is frequent in intensive care patients and can be due to several causes. However, sepsis has not been examined as a possible cause. The aim of this study is to assess the influence of experimental sepsis on hearing thresholds and to evaluate pathological changes in the cochlea....

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Main Authors: Joachim Schmutzhard, Rudolf Glueckert, Christian Pritz, Michael J. F. Blumer, Mario Bitsche, Peter Lackner, Manfred Fille, Herbert Riechelmann, Matthias Harkamp, Thongrong Sitthisak, Annelies Schrott-Fischer
Format: Article
Language:English
Published: The Company of Biologists 2013-05-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/3/745