Metabolism of propionic acid to a novel acyl-coenzyme A thioester by mammalian cell lines and platelets[S]
Metabolism of propionate involves the activated acyl-thioester propionyl-CoA intermediate. We employed LC-MS/MS, LC-selected reaction monitoring/MS, and LC-high-resolution MS to investigate metabolism of propionate to acyl-CoA intermediates. We discovered that propionyl-CoA can serve as a precursor...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520356479 |