Specificity of CD8<sup>+</sup> T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya

Specificity of CD8<sup>+</sup> T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya

Sub-Saharan Africa carries the biggest burden of the human immunodeficiency virus type 1 (HIV-1)/AIDS epidemic and is in an urgent need of an effective vaccine. CD8<sup>+</sup> T cells are an important component of the host immune response to HIV-1 and may need to be harnessed if a vacci...

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Bibliographic Details
Main Authors: Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Francesca Siliquini, Zara Hannoun, Alison Crook, Peter Hayes, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, Tomáš Hanke
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
HIV vaccine
HIVconsv
conserved regions
CD8 epitopes
HLA class I epitopes
T cell vaccine
Online Access:https://www.mdpi.com/2076-393X/8/2/260

Internet

https://www.mdpi.com/2076-393X/8/2/260

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