Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells

In our previous paper, we showed that three primaquine-cinnamic acid conjugates composed of primaquine (PQ) residue and cinnamic acid derivatives (CADs) bound directly by an amide linkage (1) or through an acylsemicarbazide spacer (2 and 3) had significant growth inhibitory effects on some cancer ce...

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Bibliographic Details
Main Authors: Mabeta Peace, Pavić Kristina, Zorc Branka
Format: Article
Language:English
Published: Sciendo 2018-09-01
Series:Acta Pharmaceutica
Subjects:
bad
p53
Online Access:https://doi.org/10.2478/acph-2018-0021