Mutation and Epistasis in Influenza Virus Evolution
Influenza remains a persistent public health challenge, because the rapid evolution of influenza viruses has led to marginal vaccine efficacy, antiviral resistance, and the annual emergence of novel strains. This evolvability is driven, in part, by the virus’s capacity to generate diversit...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-08-01
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Series: | Viruses |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4915/10/8/407 |