Anti-Inflammatory and Neuromodulatory Effects Induced by <i>Tanacetum parthenium</i> Water Extract: Results from In Silico, In Vitro and Ex Vivo Studies

Anti-Inflammatory and Neuromodulatory Effects Induced by <i>Tanacetum parthenium</i> Water Extract: Results from In Silico, In Vitro and Ex Vivo Studies

<i>Tanacetum parthenium</i> (feverfew) has traditionally been employed as a phytotherapeutic remedy in the treatment of migraine. In this study, a commercial <i>T. parthenium</i> water extract was investigated to explore its anti-inflammatory and neuromodulatory effects. Isol...

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Bibliographic Details
Main Authors: Lucia Recinella, Annalisa Chiavaroli, Viviana di Giacomo, Marco Daniel Antolini, Alessandra Acquaviva, Sheila Leone, Luigi Brunetti, Luigi Menghini, Gunes Ak, Gokhan Zengin, Simonetta Cristina Di Simone, Claudio Ferrante, Giustino Orlando
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
<i>Tanacetum parthenium</i>
cortical spreading depression
hypothalamus
interleukins
brain-derived neurotrophic factor
dopamine
Online Access:https://www.mdpi.com/1420-3049/26/1/22

Internet

https://www.mdpi.com/1420-3049/26/1/22

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