Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance

Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance

Abstract Background Osteosarcoma is the most common bone malignancy in children and adolescents, and 20%–30% of the patients suffer from poor prognosis because of individual chemoresistance. The Hippo/yes-associated protein (YAP) signaling pathway has been shown to play a role in tumor chemoresistan...

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Bibliographic Details
Main Authors: Dong-Yu Wang, Ya-Nan Wu, Jun-Qi Huang, Wei Wang, Meng Xu, Jin-Peng Jia, Gang Han, Bei-Bei Mao, Wen-Zhi Bi
Format: Article
Language:English
Published: BMC 2016-05-01
Series:Chinese Journal of Cancer
Subjects:
Hippo
YAP
Methotrexate
Doxorubicin
Osteosarcoma
Chemoresistance
Online Access:http://link.springer.com/article/10.1186/s40880-016-0109-z

Internet

http://link.springer.com/article/10.1186/s40880-016-0109-z

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