Characterization of Procoagulant COAT Platelets in Patients with Glanzmann Thrombasthenia

Characterization of Procoagulant COAT Platelets in Patients with Glanzmann Thrombasthenia

Patients affected by the rare Glanzmann thrombasthenia (GT) suffer from defective or low levels of the platelet-associated glycoprotein (GP) IIb/IIIa, which acts as a fibrinogen receptor, and have therefore an impaired ability to aggregate platelets. Because the procoagulant activity is a dichotomou...

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Bibliographic Details
Main Authors: Alessandro Aliotta, Manuel Krüsi, Debora Bertaggia Calderara, Maxime G. Zermatten, Francisco J. Gomez, Ana P. Batista Mesquita Sauvage, Lorenzo Alberio
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
procoagulant platelets
Glanzmann thrombasthenia
procoagulant activity
ion fluxes
Online Access:https://www.mdpi.com/1422-0067/21/24/9515

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https://www.mdpi.com/1422-0067/21/24/9515

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