Cav3.2 T-type calcium channels control acute itch in mice

Cav3.2 T-type calcium channels control acute itch in mice

Abstract Cav3.2 T-type calcium channels are important mediators of nociceptive signaling, but their roles in the transmission of itch remains poorly understood. Here we report a key involvement of these channels as key modulators of itch/pruritus-related behavior. We compared scratching behavior res...

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Bibliographic Details
Main Authors: Vinicius M. Gadotti, Joanna M. Kreitinger, Nicholas B. Wageling, Dylan Budke, Philippe Diaz, Gerald W. Zamponi
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Molecular Brain
Subjects:
Itch
Pruritus
Histamine
Chloroquine
Cav3.2 T-type channel
Online Access:http://link.springer.com/article/10.1186/s13041-020-00663-9

Internet

http://link.springer.com/article/10.1186/s13041-020-00663-9

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