Problems of subgroup analysis in randomized controlled trial
Abstract Multiple subgroup analyses of the same data increase the risk of generating false positive findings. All outcomes and planned subgroup analyses should thus be prespecified and described in the original trial registry. When outcome changes during an ongoing trial seem justifiable, publicatio...
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | BMC Anesthesiology |
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| Online Access: | http://link.springer.com/article/10.1186/s12871-020-01105-8 |