Structural principles of SNARE complex recognition by the AAA+ protein NSF

Structural principles of SNARE complex recognition by the AAA+ protein NSF

The recycling of SNARE proteins following complex formation and membrane fusion is an essential process in eukaryotic trafficking. A highly conserved AAA+ protein, NSF (N-ethylmaleimide sensitive factor) and an adaptor protein, SNAP (soluble NSF attachment protein), disassemble the SNARE complex. We...

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Bibliographic Details
Main Authors: K Ian White, Minglei Zhao, Ucheor B Choi, Richard A Pfuetzner, Axel T Brunger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
synaptic vesicle recycling
neurotransmitter release
SNARE complex disassembly
ATPase
electron cryomicroscopy
Online Access:https://elifesciences.org/articles/38888

Internet

https://elifesciences.org/articles/38888

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