Innate and adaptive immune traits are differentially affected by genetic and environmental factors

Innate and adaptive immune traits are differentially affected by genetic and environmental factors

Both genetics and environment affect the number and phenotype of immune cells. Here the authors characterize the degree of influence of genetics versus environment on various immune cell parameters by analysing a large cohort of female twins.

Bibliographic Details
Main Authors: Massimo Mangino, Mario Roederer, Margaret H. Beddall, Frank O. Nestle, Tim D. Spector
Format: Article
Language:English
Published: Nature Publishing Group 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13850
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spelling doaj-16f6257f95c540d1a3c35d6f7b8910952021-05-11T07:53:01ZengNature Publishing GroupNature Communications2041-17232017-01-01811710.1038/ncomms13850Innate and adaptive immune traits are differentially affected by genetic and environmental factorsMassimo Mangino0Mario Roederer1Margaret H. Beddall2Frank O. Nestle3Tim D. Spector4Department of Twin Research and Genetic Epidemiology, Kings College LondonImmunoTechnology Section, Vaccine Research Center, NIAID, NIHImmunoTechnology Section, Vaccine Research Center, NIAID, NIHNIHR Biomedical Research Centre at Guy’s and St Thomas’ Foundation TrustDepartment of Twin Research and Genetic Epidemiology, Kings College LondonBoth genetics and environment affect the number and phenotype of immune cells. Here the authors characterize the degree of influence of genetics versus environment on various immune cell parameters by analysing a large cohort of female twins.https://doi.org/10.1038/ncomms13850
collection DOAJ
language English
format Article
sources DOAJ
author Massimo Mangino
Mario Roederer
Margaret H. Beddall
Frank O. Nestle
Tim D. Spector
spellingShingle Massimo Mangino
Mario Roederer
Margaret H. Beddall
Frank O. Nestle
Tim D. Spector
Innate and adaptive immune traits are differentially affected by genetic and environmental factors
Nature Communications
author_facet Massimo Mangino
Mario Roederer
Margaret H. Beddall
Frank O. Nestle
Tim D. Spector
author_sort Massimo Mangino
title Innate and adaptive immune traits are differentially affected by genetic and environmental factors
title_short Innate and adaptive immune traits are differentially affected by genetic and environmental factors
title_full Innate and adaptive immune traits are differentially affected by genetic and environmental factors
title_fullStr Innate and adaptive immune traits are differentially affected by genetic and environmental factors
title_full_unstemmed Innate and adaptive immune traits are differentially affected by genetic and environmental factors
title_sort innate and adaptive immune traits are differentially affected by genetic and environmental factors
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-01-01
description Both genetics and environment affect the number and phenotype of immune cells. Here the authors characterize the degree of influence of genetics versus environment on various immune cell parameters by analysing a large cohort of female twins.
url https://doi.org/10.1038/ncomms13850
work_keys_str_mv AT massimomangino innateandadaptiveimmunetraitsaredifferentiallyaffectedbygeneticandenvironmentalfactors
AT marioroederer innateandadaptiveimmunetraitsaredifferentiallyaffectedbygeneticandenvironmentalfactors
AT margarethbeddall innateandadaptiveimmunetraitsaredifferentiallyaffectedbygeneticandenvironmentalfactors
AT frankonestle innateandadaptiveimmunetraitsaredifferentiallyaffectedbygeneticandenvironmentalfactors
AT timdspector innateandadaptiveimmunetraitsaredifferentiallyaffectedbygeneticandenvironmentalfactors
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