Ultrasensitive detection of lipoarabinomannan with plasmonic grating biosensors in clinical samples of HIV negative patients with tuberculosis.

BACKGROUND:Timely diagnosis of tuberculosis disease is critical for positive patient outcomes, yet potentially millions go undiagnosed or unreported each year. Sputum is widely used as the testing input, but limited by its complexity, heterogeneity, and sourcing problems. Finding methods to interrog...

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Bibliographic Details
Main Authors: Aaron Wood, Syed Barizuddin, Charles M Darr, Cherian J Mathai, Alexey Ball, Kyle Minch, Akos Somoskovi, Beston Hamasur, John T Connelly, Bernhard Weigl, Alfred Andama, Adithya Cattamanchi, Keshab Gangopadhyay, Sangho Bok, Shubhra Gangopadhyay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214161