Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients.

Immunoglobulin-like transcript (ILT) 3 and 4 are inhibitory receptors that modulate immune responses. Their expression has been reported to be affected by interferon, offering a possible mechanism by which this cytokine exerts its therapeutic effect in multiple sclerosis, a condition thought to invo...

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Bibliographic Details
Main Authors: Anne Waschbisch, Nicholas Sanderson, Markus Krumbholz, George Vlad, Diethilde Theil, Stefan Schwab, Mathias Mäurer, Tobias Derfuss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4281069?pdf=render