DNA abasic site-selective enhancement of sanguinarine fluorescence with a large emission shift.

Small molecules that can specifically bind to a DNA abasic site (AP site) have received much attention due to their importance in DNA lesion identification, drug discovery, and sensor design. Herein, the AP site binding behavior of sanguinarine (SG), a natural alkaloid, was investigated. In aqueous...

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Bibliographic Details
Main Authors: Fei Wu, Yanwei Sun, Yong Shao, Shujuan Xu, Guiying Liu, Jian Peng, Lingling Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3502418?pdf=render