Two Modes of the Axonal Interferon Response Limit Alphaherpesvirus Neuroinvasion
Infection by alphaherpesviruses, including herpes simplex virus (HSV) and pseudorabies virus (PRV), typically begins at epithelial surfaces and continues into the peripheral nervous system (PNS). Inflammatory responses are induced at the infected peripheral site prior to invasion of the PNS. When th...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2016-02-01
|
Series: | mBio |
Online Access: | http://mbio.asm.org/cgi/content/full/7/1/e02145-15 |