Two Modes of the Axonal Interferon Response Limit Alphaherpesvirus Neuroinvasion

Infection by alphaherpesviruses, including herpes simplex virus (HSV) and pseudorabies virus (PRV), typically begins at epithelial surfaces and continues into the peripheral nervous system (PNS). Inflammatory responses are induced at the infected peripheral site prior to invasion of the PNS. When th...

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Bibliographic Details
Main Authors: Ren Song, Orkide O. Koyuncu, Todd M. Greco, Benjamin A. Diner, Ileana M. Cristea, Lynn W. Enquist
Format: Article
Language:English
Published: American Society for Microbiology 2016-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/1/e02145-15