Contact residue contributions to interaction energies between SARS-CoV-1 spike proteins and human ACE2 receptors

Abstract Several viruses of the corona family interact, via their spike (S) proteins, with human cellular receptors. Spike proteins of SARS-CoV-1 and SARS-CoV-2 virions, being structurally related but not identical, mediate attachment to the human angiotensin-converting enzyme 2 (hACE2) receptor in...

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Bibliographic Details
Main Authors: Jorge H. Rodriguez, Akshita Gupta
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80942-6