Uptake of the necrotic serpin in Drosophila melanogaster via the lipophorin receptor-1.
The humoral response to fungal and Gram-positive infections is regulated by the serpin-family inhibitor, Necrotic. Following immune-challenge, a proteolytic cascade is activated which signals through the Toll receptor. Toll activation results in a range of antibiotic peptides being synthesised in th...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-06-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2694266?pdf=render |