Granulocyte Colony Stimulating Factor (GCSF) Can Attenuate Neuropathic Pain by Suppressing Monocyte Chemoattractant Protein-1 (MCP-1) Expression, through Upregulating the Early MicroRNA-122 Expression in the Dorsal Root Ganglia

Granulocyte Colony Stimulating Factor (GCSF) Can Attenuate Neuropathic Pain by Suppressing Monocyte Chemoattractant Protein-1 (MCP-1) Expression, through Upregulating the Early MicroRNA-122 Expression in the Dorsal Root Ganglia

Our previous animal studies and several human clinical trials have shown that granulocyte-colony stimulating factor (GCSF) can attenuate neuropathic pain through various mechanisms. GCSF itself is also a multipotent cytokine that can modulate microribonucleic acid (microRNA) expression profiles in v...

Full description

Bibliographic Details
Main Authors: Ming-Feng Liao, Jung-Lung Hsu, Kwok-Tung Lu, Po-Kuan Chao, Mei-Yun Cheng, Hui-Ching Hsu, Ai-Lun Lo, Yun-Lin Lee, Yu-Hui Hung, Rong-Kuo Lyu, Hung-Chou Kuo, Chun-Che Chu, Long-Sun Ro
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
chronic constriction injury
neuropathic pain
granulocyte colony stimulating factor
microRNA-122
monocyte chemoattractant protein-1
dorsal root ganglia
Online Access:https://www.mdpi.com/2073-4409/9/7/1669

Internet

https://www.mdpi.com/2073-4409/9/7/1669

Similar Items