Evolution and thermodynamics of the slow unfolding of hyperstable monomeric proteins

<p>Abstract</p> <p>Background</p> <p>The unfolding speed of some hyperthermophilic proteins is dramatically lower than that of their mesostable homologs. Ribonuclease HII from the hyperthermophilic archaeon <it>Thermococcus kodakaraensis </it>(Tk-RNase HII)...

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Bibliographic Details
Main Authors: Koga Yuichi, Chon Hyongi, You Dong-Ju, Tadokoro Takashi, Mukaiyama Atsushi, Okamoto Tomohiro, Okada Jun, Takano Kazufumi, Kanaya Shigenori
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/207