Glycan-mediated enhancement of reovirus receptor binding

Glycan-mediated enhancement of reovirus receptor binding

The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cel...

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Bibliographic Details
Main Authors: Melanie Koehler, Pavithra Aravamudhan, Camila Guzman-Cardozo, Andra C. Dumitru, Jinsung Yang, Serena Gargiulo, Patrice Soumillion, Terence S. Dermody, David Alsteens
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12411-2

Internet

https://doi.org/10.1038/s41467-019-12411-2

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