Ex vivo multi-electrode analysis reveals spatiotemporal dynamics of ictal behavior at the infiltrated margin of glioma

Ex vivo multi-electrode analysis reveals spatiotemporal dynamics of ictal behavior at the infiltrated margin of glioma

The purpose of this study is to develop a platform in which the cellular and molecular underpinnings of chronic focal neocortical lesional epilepsy can be explored and use it to characterize seizure-like events (SLEs) in an ex vivo model of infiltrating high-grade glioma. Microelectrode arrays were...

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Bibliographic Details
Main Authors: Brian J.A. Gill, Xiaoping Wu, Farhan A. Khan, Alexander A. Sosunov, Jyun-you Liou, Athanassios Dovas, Tahra L. Eissa, Matei A. Banu, Lisa M. Bateman, Guy M. McKhann, II, Peter Canoll, Catherine Schevon
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Glioma
Epilepsy
Seizure
Microelectrode array
Zero magnesium
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303511

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http://www.sciencedirect.com/science/article/pii/S0969996119303511

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