Clinical Effects of Krachaidum (): A Systematic Review

Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and su...

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Main Authors: Surasak Saokaew PharmD, PhD, Preyanate Wilairat PharmD, Paranya Raktanyakan PharmD, Piyameth Dilokthornsakul PharmD, PhD, Teerapon Dhippayom PharmD, PhD, Chuenjid Kongkaew PhD, Rosarin Sruamsiri MBA, PhD, Anchalee Chuthaputti PhD, Nathorn Chaiyakunapruk PharmD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2017-07-01
Series:Journal of Evidence-Based Complementary & Alternative Medicine
Online Access:https://doi.org/10.1177/2156587216669628
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spelling doaj-191a6397215e4550a11e5e8e24846d232020-11-25T01:49:37ZengSAGE PublishingJournal of Evidence-Based Complementary & Alternative Medicine2156-58722156-58992017-07-012210.1177/2156587216669628Clinical Effects of Krachaidum (): A Systematic ReviewSurasak Saokaew PharmD, PhD0Preyanate Wilairat PharmD1Paranya Raktanyakan PharmD2Piyameth Dilokthornsakul PharmD, PhD3Teerapon Dhippayom PharmD, PhD4Chuenjid Kongkaew PhD5Rosarin Sruamsiri MBA, PhD6Anchalee Chuthaputti PhD7Nathorn Chaiyakunapruk PharmD, PhD8 Naresuan University, Phitsanulok, Thailand University of Phayao, Phayao, Thailand University of Phayao, Phayao, Thailand Naresuan University, Phitsanulok, Thailand Naresuan University, Phitsanulok, Thailand Naresuan University, Phitsanulok, Thailand Naresuan University, Phitsanulok, Thailand Department for Development of Thai Traditional and Alternative Medicine, Ministry of Public Health, Nonthaburi, Thailand University of Wisconsin–Madison, WI, USAKaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.https://doi.org/10.1177/2156587216669628
collection DOAJ
language English
format Article
sources DOAJ
author Surasak Saokaew PharmD, PhD
Preyanate Wilairat PharmD
Paranya Raktanyakan PharmD
Piyameth Dilokthornsakul PharmD, PhD
Teerapon Dhippayom PharmD, PhD
Chuenjid Kongkaew PhD
Rosarin Sruamsiri MBA, PhD
Anchalee Chuthaputti PhD
Nathorn Chaiyakunapruk PharmD, PhD
spellingShingle Surasak Saokaew PharmD, PhD
Preyanate Wilairat PharmD
Paranya Raktanyakan PharmD
Piyameth Dilokthornsakul PharmD, PhD
Teerapon Dhippayom PharmD, PhD
Chuenjid Kongkaew PhD
Rosarin Sruamsiri MBA, PhD
Anchalee Chuthaputti PhD
Nathorn Chaiyakunapruk PharmD, PhD
Clinical Effects of Krachaidum (): A Systematic Review
Journal of Evidence-Based Complementary & Alternative Medicine
author_facet Surasak Saokaew PharmD, PhD
Preyanate Wilairat PharmD
Paranya Raktanyakan PharmD
Piyameth Dilokthornsakul PharmD, PhD
Teerapon Dhippayom PharmD, PhD
Chuenjid Kongkaew PhD
Rosarin Sruamsiri MBA, PhD
Anchalee Chuthaputti PhD
Nathorn Chaiyakunapruk PharmD, PhD
author_sort Surasak Saokaew PharmD, PhD
title Clinical Effects of Krachaidum (): A Systematic Review
title_short Clinical Effects of Krachaidum (): A Systematic Review
title_full Clinical Effects of Krachaidum (): A Systematic Review
title_fullStr Clinical Effects of Krachaidum (): A Systematic Review
title_full_unstemmed Clinical Effects of Krachaidum (): A Systematic Review
title_sort clinical effects of krachaidum (): a systematic review
publisher SAGE Publishing
series Journal of Evidence-Based Complementary & Alternative Medicine
issn 2156-5872
2156-5899
publishDate 2017-07-01
description Kaempferia parviflora (Krachaidum) is a medicinal plant in the family Zingiberaceae. Its rhizome has been used as folk medicine for many centuries. A number of pharmacological studies of Krachaidum had claimed benefits for various ailments. Therefore, this study aimed to systematically search and summarize the clinical evidences of Krachaidum in all identified indications. Of 683 records identified, 7 studies were included. From current clinical trials, Krachaidum showed positive benefits but remained inconclusive since small studies were included. Even though results found that Krachaidum significantly increased hand grip strength and enhanced sexual erotic stimuli, these were based on only 2 studies and 1 study, respectively. With regard to harmful effects, we found no adverse events reported even when Krachaidum 1.35 g/day was used. Therefore, future studies of Krachaidum are needed with regards to both safety and efficacy outcomes.
url https://doi.org/10.1177/2156587216669628
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