Cyanidin-3-glucoside activates Nrf2-antioxidant response element and protects against glutamate-induced oxidative and endoplasmic reticulum stress in HT22 hippocampal neuronal cells

Cyanidin-3-glucoside activates Nrf2-antioxidant response element and protects against glutamate-induced oxidative and endoplasmic reticulum stress in HT22 hippocampal neuronal cells

Abstract Background Cyanidin-3-glucoside (C3G), a major anthocyanin present in berries, exhibits a strong antioxidant and has been shown to possess a neuroprotection. Prolonged exposure to glutamate will lead to oxidative damage and endoplasmic reticulum stress which could play a key detrimental rol...

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Bibliographic Details
Main Authors: Monruedee Sukprasansap, Pithi Chanvorachote, Tewin Tencomnao
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Cyanidin-3-glucoside
Anthocyanin
Oxidative stress
ER stress
Glutamate
Nrf2
Online Access:https://doi.org/10.1186/s12906-020-2819-7

Internet

https://doi.org/10.1186/s12906-020-2819-7

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