PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients

PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients

Introduction Patients who sustain orthopaedic trauma are at an increased risk of venous thromboembolism (VTE), including fatal pulmonary embolism (PE). Current guidelines recommend low-molecular-weight heparin (LMWH) for VTE prophylaxis in orthopaedic trauma patients. However, emerging literature in...

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Main Authors: Deborah M Stein, Gregory J Jurkovich, Elliott R Haut, Rishi Rattan, Bellal Joseph, Theodore T Manson, Yasmin Degani, Debra Marvel, Heather A Vallier, Paul S. Whiting, Robert V O'Toole, Samuel Z Goldhaber, Joseph Cuschieri, Katherine P Frey, Nathan N O'Hara, Daniel O Scharfstein, Gerard P Slobogean, Tara J Taylor, Bryce E Haac, Anthony R Carlini, Kuladeep Sudini, Stephen T Wegener, Reza Firoozabadi, Michael J Bosse, Rachel B Seymour, Martha B Holden, Ida Leah Gitajn, Alexander L Eastman, Joshua L Gary, Conor P Kleweno, Renan C Castillo, Gregory T. Altman, A Britton Christmas, Robert A. Hymes, Greg E. Gaski, Roman M. Natoli, George C. Velmahos, Michael J. Weaver, Bryan A. Cotton, Herman Johal, Niv Sne, Roman Hayda, Andrew R. Evans, Patrick M. Osborn, Jessica C. Rivera, Christina L. Boulton, Prism S. Schneider, Patrick F. Bergin, Matthew E. Kutcher, Martin A. Croce, John C. Weinlein, William Obremskey, Oscar D. Guillamondegui, Eben A. Carroll, Preston R. Miller
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/3/e041845.full

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https://bmjopen.bmj.com/content/11/3/e041845.full

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