Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis

Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis

Context Guizhi-Shaoyao-Zhimu decoction (GSZD) is commonly used to treat rheumatoid arthritis (RA), but its mechanism is unclear. Objective To investigate the effect of GSZD on bone erosion in type II collagen (CII)-induced arthritis (CIA) in rats and to identify the underlying mechanism. Materials a...

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Bibliographic Details
Main Authors:	Shu-jun Wei, Qing Zhang, Yong-jing Xiang, Lan-yu Peng, Wei Peng, Qiang Ren, Yong-xiang Gao
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2021-01-01
Series:	Pharmaceutical Biology
Subjects:	rheumatoid arthritis osteoclast rankl osteoprotegerin
Online Access:	http://dx.doi.org/10.1080/13880209.2021.1876100

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