In Vivo Gene Essentiality and Metabolism in Bordetella pertussis

In Vivo Gene Essentiality and Metabolism in Bordetella pertussis

Our study describes the first in vivo transposon sequencing (Tn-seq) analysis of B. pertussis and identifies genes predicted to be essential for in vivo growth in a murine model of intranasal infection, generating key resources for future investigations into B. pertussis pathogenesis and vaccine des...

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Bibliographic Details
Main Authors: Laura A. Gonyar, Patrick E. Gelbach, Dennis G. McDuffie, Alexander F. Koeppel, Qing Chen, Gloria Lee, Louise M. Temple, Scott Stibitz, Erik L. Hewlett, Jason A. Papin, F. Heath Damron, Joshua C. Eby
Format: Article
Language:English
Published: American Society for Microbiology 2019-05-01
Series:mSphere
Subjects:
Bordetella
Bordetella pertussis
Tn-seq
gene essentiality
in vivo
metabolism
Online Access:https://doi.org/10.1128/mSphere.00694-18

Internet

https://doi.org/10.1128/mSphere.00694-18

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