Enantiomeric Separation and Determination of the Enantiomeric Impurity of Armodafinil by Capillary Electrophoresis with Sulfobutyl Ether-β-cyclodextrin as Chiral Selector

A selective capillary electrophoresis method using sulfobutyl ether-β-cyclodextrin as a chiral selector was developed and validated for the determination of the enantiomeric impurity of (R)-modafinil, i.e., armodafinil. Several parameters were optimized for a satisfactory enantioresolution, includin...

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Bibliographic Details
Main Authors: Bingren Xiang, Yibing Ji, Suyun Xiang, Xiaojuan Zhou, Wei Wang
Format: Article
Published: MDPI AG 2011-12-01
Online Access:http://www.mdpi.com/1420-3049/17/1/303/