Study of Antiulcer Activity of Bauhinia racemosa lam in Rats

• Main Authors: V.I. Borikar, C.R. Jangde, Preety Philip, D.S. Rekhe and S.K. Atole
• Format: Article
• Language: English
• Published: Veterinary World 2009-12-01
• Series: Veterinary World
• Subjects: Bauhinia racemosa; Paracetamol; antiulcer activity
• Online Access: http://www.scopemed.org/fulltextpdf.php?mno=934

An experiment was conducted to study the antiulcer effect of the dried fruit powder of the plant Bauhinia racemosa in Wistar albino rats. Thirty Wistar rats of either sex weighing between 150 - 200gm were selected and divided into five groups, each comprising of six rats. The rats were divided into 5 groups T1T2, T3, T4, and T5 and were given 0.5 ml normal saline, aqueous extract in the dose rate of100mg/kg body weight, 200mg/kg body weight, alcoholic extract @100mg/kg body weight and 200mg/kg body weight respectively. After one hour all the groups were administered Paracetamol at a dose rate of 200mg/kg body weight orally. After 24hrs, the number of ulcers, ulcer score, percent incidence, ulcer index and healing index were recorded. From the results obtained it was concluded that aqueous extract in the dose rate of 200mg/kg body weight and alcoholic extract (100mg/kg & 200mg/kg body weight) could produce antiulcer activity. [Vet World 2009; 2(6.000): 217-218]