The biological role of arachidonic acid 12-lipoxygenase (ALOX12) in various human diseases

ALOX12 encodes arachidonic acid 12-lipoxygenase that acts on different polyunsaturated fatty acid substrates to produce biologically active lipid mediators including eicosanes and lipoxins. ALOX12 protein plays an important role in inflammation and oxidation, while abnormal DNA methylation and genet...

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Bibliographic Details
Main Authors: Zhonghua Zheng, Yin Li, Gehui Jin, Tianyi Huang, Mengsha Zou, Shiwei Duan
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220305473