Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes

Background: Early identification of severe dengue patients is important regarding patient management and resource allocation. We investigated the association of 10 biomarkers (VCAM-1, SDC-1, Ang-2, IL-8, IP-10, IL-1RA, sCD163, sTREM-1, ferritin, CRP) with the development of severe/moderate dengue (S...

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Main Authors: Nguyen Lam Vuong, Phung Khanh Lam, Damien Keng Yen Ming, Huynh Thi Le Duyen, Nguyet Minh Nguyen, Dong Thi Hoai Tam, Kien Duong Thi Hue, Nguyen VV Chau, Ngoun Chanpheaktra, Lucy Chai See Lum, Ernesto Pleités, Cameron P Simmons, Kerstin D Rosenberger, Thomas Jaenisch, David Bell, Nathalie Acestor, Christine Halleux, Piero L Olliaro, Bridget A Wills, Ronald B Geskus, Sophie Yacoub
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/67460