Oral Treatment with RD2RD2 Impedes Development of Motoric Phenotype and Delays Symptom Onset in SOD1<sup>G93A</sup> Transgenic Mice
Neuroinflammation is a pathological hallmark of several neurodegenerative disorders and plays a key role in the pathogenesis of amyotrophic lateral sclerosis (ALS). It has been implicated as driver of disease progression and is observed in ALS patients, as well as in the transgenic SOD1<sup>G9...
Main Authors: | Julia Post, Anja Schaffrath, Ian Gering, Sonja Hartwig, Stefan Lehr, N. Jon Shah, Karl-Josef Langen, Dieter Willbold, Janine Kutzsche, Antje Willuweit |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/13/7066 |
Similar Items
-
A Novel Anti-Inflammatory <span style="font-variant: small-caps">d</span>-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model
by: Julia Post, et al.
Published: (2021-03-01) -
Do We Need Anti-Prion Compounds to Treat Alzheimer’s Disease?
by: Dieter Willbold, et al.
Published: (2019-06-01) -
In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-<span style="font-variant: small-caps">d</span>-Enantiomeric Peptide Developed for the Treatment of Alzheimer’s Disease
by: Sarah Schemmert, et al.
Published: (2021-06-01) -
Deceleration of the neurodegenerative phenotype in pyroglutamate-Aβ accumulating transgenic mice by oral treatment with the Aβ oligomer eliminating compound RD2
by: Sarah Schemmert, et al.
Published: (2019-04-01) -
Production of Magnetic Monopoles via Photon Fusion: Implementation in <span style="font-variant: small-caps;">MadGraph <sup>†</sup><br /></span>
by: Arka Santra
Published: (2019-05-01)