Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome

We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patie...

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Main Authors: Rabindra P. Singh, Robert J. Grimer, Nabina Bhujel, Simon R. Carter, Roger M. Tillman, Adesegun Abudu
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2008/654987
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spelling doaj-1aaed435a70d4eabbd4d1b88df289f3c2020-11-24T23:37:16ZengHindawi LimitedSarcoma1357-714X1369-16432008-01-01200810.1155/2008/654987654987Adult Head and Neck Soft Tissue Sarcomas: Treatment and OutcomeRabindra P. Singh0Robert J. Grimer1Nabina Bhujel2Simon R. Carter3Roger M. Tillman4Adesegun Abudu5King's College Hospital, Denmark Hill, London SE5 9RS, UKRoyal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UKOral and Maxillofacial Surgery, University Hospitals Birmingham, Birmingham B15 2TH, UKRoyal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UKRoyal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UKRoyal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UKWe have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.http://dx.doi.org/10.1155/2008/654987
collection DOAJ
language English
format Article
sources DOAJ
author Rabindra P. Singh
Robert J. Grimer
Nabina Bhujel
Simon R. Carter
Roger M. Tillman
Adesegun Abudu
spellingShingle Rabindra P. Singh
Robert J. Grimer
Nabina Bhujel
Simon R. Carter
Roger M. Tillman
Adesegun Abudu
Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
Sarcoma
author_facet Rabindra P. Singh
Robert J. Grimer
Nabina Bhujel
Simon R. Carter
Roger M. Tillman
Adesegun Abudu
author_sort Rabindra P. Singh
title Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_short Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_full Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_fullStr Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_full_unstemmed Adult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
title_sort adult head and neck soft tissue sarcomas: treatment and outcome
publisher Hindawi Limited
series Sarcoma
issn 1357-714X
1369-1643
publishDate 2008-01-01
description We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.
url http://dx.doi.org/10.1155/2008/654987
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