Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R

Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R

Pigment epithelial-derived factor (PEDF) is known as a widely expressed multifunctional secreted glycoprotein whose biological actions are cell-type dependent. Recent studies demonstrated that PEDF displays cytoprotective activity in several cell types. However, it remains unknown whether PEDF is in...

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Bibliographic Details
Main Authors: Shengcheng Yao, Yingnan Zhang, Xiaoyu Wang, Fengchao Zhao, Maji Sun, Xin Zheng, Hongyan Dong, Kaijin Guo
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
Subjects:
pigment epithelium-derived factor
glucocorticoids
apoptosis
pigment epithelium-derived factor receptor
lysophosphatidic acid
PI3K/Akt signaling
Online Access:http://www.mdpi.com/1422-0067/17/5/730

Internet

http://www.mdpi.com/1422-0067/17/5/730

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