Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro
Objectives: To compare in vitro the effect of a toothpaste containing fluoride (F), calcium silicate (CaSi) and sodium phosphate salts to conventional toothpaste (NaF) on human enamel specimens submitted to erosive and abrasive challenges. Methods: 48 sound and 48 enamel samples pre-treated with 1%...
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2021-04-01
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doaj-1ab4ea9eb70a4f728087048efaabeeb32021-05-03T10:25:52ZengElsevierHeliyon2405-84402021-04-0174e06741Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitroMarília Afonso Rabelo Buzalaf0Flávia Mauad Levy1Beatriz Gomes2Aline Dionizio Valle3Juliana Sanches Trevizol4Ana Carolina Magalhães5Andrew Joiner6Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, Brazil; Corresponding author.Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, BrazilDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, BrazilDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, BrazilDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, BrazilDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, 17012-901, Bauru, SP, BrazilUnilever Oral Care, Quarry Road East, Bebington, Wirral, CH63 3JW, United KingdomObjectives: To compare in vitro the effect of a toothpaste containing fluoride (F), calcium silicate (CaSi) and sodium phosphate salts to conventional toothpaste (NaF) on human enamel specimens submitted to erosive and abrasive challenges. Methods: 48 sound and 48 enamel samples pre-treated with 1% citric acid were divided into 4 groups (n = 12): Group 1- Non-fluoride toothpaste; Group 2- NaF toothpaste (1450 ppmF); Group 3- CaSi toothpaste (1450 ppmF; MFP); Group 4- Erosion only. The samples were subjected to pH cycling (3 cycles/day; 90s; 1% citric acid, pH 3.6) and to abrasion for 7 days. After the 1st and the last cycle, they were submitted to abrasion (15s, 1.5N load), using a brushing machine, soft toothbrush and toothpaste slurry (1:3; 15ml/sample) and then immersed in the slurry for 45s. Samples were immersed in artificial saliva between the challenges. Enamel loss was evaluated using profilometry on days 3 and 7. Data were analysed by ANOVA and Tukey's test (p < 0.05). Results: For sound enamel at baseline, mean (±SD) enamel loss (μm) for groups 1–4 on day 3 was 2.15 ± 0.35a, 1.20 ± 0.22b, 0.95 ± 0.19b and 1.98 ± 0.32a; on day 7 was 3.05 ± 0.40a, 2.07 ± 0.32b, 1.36 ± 0.33c and 3.69 ± 0.27d respectively. For acid-softened enamel at baseline, enamel loss on day 3 was 3.16 ± 0.19a, 2.17 ± 0.14b, 1.70 ± 0.11c and 3.04 ± 0.19a; on day 7 was 3.92 ± 0.25a, 3.07 ± 0.13b, 2.09 ± 0.15c and 3.87 ± 0.25a respectively. Conclusions: Both F toothpastes led to significantly higher enamel protection from short-term erosion and abrasion in comparison to the non-F toothpaste and erosion only. In the longer term, CaSi toothpaste conferred significantly higher protection than NaF toothpaste. Clinical significance: The results showed that for the longer term the CaSi toothpaste provided significantly higher protection than the NaF toothpaste, which indicates a good potential of the former to help prevent erosive tooth wear.http://www.sciencedirect.com/science/article/pii/S2405844021008446EnamelErosionAbrasionToothbrushingToothpaste |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Marília Afonso Rabelo Buzalaf Flávia Mauad Levy Beatriz Gomes Aline Dionizio Valle Juliana Sanches Trevizol Ana Carolina Magalhães Andrew Joiner |
spellingShingle |
Marília Afonso Rabelo Buzalaf Flávia Mauad Levy Beatriz Gomes Aline Dionizio Valle Juliana Sanches Trevizol Ana Carolina Magalhães Andrew Joiner Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro Heliyon Enamel Erosion Abrasion Toothbrushing Toothpaste |
author_facet |
Marília Afonso Rabelo Buzalaf Flávia Mauad Levy Beatriz Gomes Aline Dionizio Valle Juliana Sanches Trevizol Ana Carolina Magalhães Andrew Joiner |
author_sort |
Marília Afonso Rabelo Buzalaf |
title |
Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
title_short |
Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
title_full |
Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
title_fullStr |
Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
title_full_unstemmed |
Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
title_sort |
protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro |
publisher |
Elsevier |
series |
Heliyon |
issn |
2405-8440 |
publishDate |
2021-04-01 |
description |
Objectives: To compare in vitro the effect of a toothpaste containing fluoride (F), calcium silicate (CaSi) and sodium phosphate salts to conventional toothpaste (NaF) on human enamel specimens submitted to erosive and abrasive challenges. Methods: 48 sound and 48 enamel samples pre-treated with 1% citric acid were divided into 4 groups (n = 12): Group 1- Non-fluoride toothpaste; Group 2- NaF toothpaste (1450 ppmF); Group 3- CaSi toothpaste (1450 ppmF; MFP); Group 4- Erosion only. The samples were subjected to pH cycling (3 cycles/day; 90s; 1% citric acid, pH 3.6) and to abrasion for 7 days. After the 1st and the last cycle, they were submitted to abrasion (15s, 1.5N load), using a brushing machine, soft toothbrush and toothpaste slurry (1:3; 15ml/sample) and then immersed in the slurry for 45s. Samples were immersed in artificial saliva between the challenges. Enamel loss was evaluated using profilometry on days 3 and 7. Data were analysed by ANOVA and Tukey's test (p < 0.05). Results: For sound enamel at baseline, mean (±SD) enamel loss (μm) for groups 1–4 on day 3 was 2.15 ± 0.35a, 1.20 ± 0.22b, 0.95 ± 0.19b and 1.98 ± 0.32a; on day 7 was 3.05 ± 0.40a, 2.07 ± 0.32b, 1.36 ± 0.33c and 3.69 ± 0.27d respectively. For acid-softened enamel at baseline, enamel loss on day 3 was 3.16 ± 0.19a, 2.17 ± 0.14b, 1.70 ± 0.11c and 3.04 ± 0.19a; on day 7 was 3.92 ± 0.25a, 3.07 ± 0.13b, 2.09 ± 0.15c and 3.87 ± 0.25a respectively. Conclusions: Both F toothpastes led to significantly higher enamel protection from short-term erosion and abrasion in comparison to the non-F toothpaste and erosion only. In the longer term, CaSi toothpaste conferred significantly higher protection than NaF toothpaste. Clinical significance: The results showed that for the longer term the CaSi toothpaste provided significantly higher protection than the NaF toothpaste, which indicates a good potential of the former to help prevent erosive tooth wear. |
topic |
Enamel Erosion Abrasion Toothbrushing Toothpaste |
url |
http://www.sciencedirect.com/science/article/pii/S2405844021008446 |
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